Food allergies occur when the body mistakenly identifies certain foods as harmful substances, prompting the immune system to react. These reactions can manifest in various ways.

IgE-mediated food allergy is the most commonly recognized type. It can cause localized swelling such as hives, itching, facial or lip swelling, difficulty breathing, or even death, depending on the severity. This type of allergy is often lifelong but does not typically affect other systems of the body.

IgG-mediated food sensitivity, also known as delayed or hidden food allergy, involves Immunoglobulin G (IgG), an antibody produced by white blood cells. Some types of IgG remain in the body for life, while others disappear over time. Therefore, IgG food sensitivities can potentially resolve on their own, although in some cases they may persist.

IgG antibodies have a unique ability to “lock onto” specific targets based on their structure. If they encounter a substance that closely resembles a previously recognized target, they will attack. Unfortunately, if a cell in the body resembles that target, IgG may mistakenly attack the body’s own cells. This can lead to chronic or unexplained symptoms depending on which tissues are affected. Symptoms may include chronic headaches, migraines, mood swings, depression, slow thinking, memory issues, insomnia, skin rashes, acne, dull complexion, premature wrinkles, chronic hives, dandruff, psoriasis, bloating, indigestion, constipation, diarrhea, intestinal inflammation, weight gain, bloating, fatigue, allergic rhinitis, nasal congestion, chronic sinusitis, and autoimmune imbalances.

Furthermore, persistent IgG-mediated reactions in the gut can cause inflammation and disrupt the balance of gut microbiota. This imbalance can reduce the number of beneficial bacteria while increasing harmful ones, affecting the gut’s ability to produce essential vitamins and hormones, weakening the intestinal barrier, and potentially leading to leaky gut syndrome. This condition can further worsen food sensitivities, creating a vicious cycle that is difficult to break.

If one is aware of their food sensitivities, avoiding the problematic foods can help stop IgG production toward those foods. With consistent avoidance, existing IgG antibodies can gradually disappear, potentially resolving the sensitivity. However, recurrence is possible if poor dietary habits return. The duration of food avoidance depends on the specific food and the persistence of IgG antibodies in the body. Generally, a 3–6 month avoidance period is recommended, followed by retesting.

At Medtopia, the IgG food sensitivity test uses Microarray technology from the UK, capable of detecting sensitivities to up to 222 types of foods using just a small blood sample, with results available within one day.